ANTIOXIDANT STUDIES ON METHANOL AND AQUEOUS EXTRACTS OF GYMNOSPORIA MONTANA PLANT
By: Ansari, Nishat.
Contributor(s): Chandel, Divya.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol.11(2).Description: 65-70p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Objective: The main objective of this study was to evaluate the free radical scavenging activity of methanol (70%) and aqueous extract of G. montana leaves which is a traditionally used herb known for its hepatoprotective activity . Method s: The in vitro antioxidant activity of G. montana extract was determined using 1, 1 -diphenyl -2-picrylhydrazyl radical (DPPH) , 2,2 ′ -azin obis - (3 -ethylbenzothiaziline -6-sulfonate (ABTS), Hydrogen p eroxide scavenging activity , Superoxide anion radical scavenging activity and Reducing Power ability at three different concentrations (1.78μg /ml , 3.57μg/ml and 7.14μg/ml ). Result s: The Result s revealed similar observations between the methanol and aqueous extract with respect to standard and showed potent antioxidant activity. Ascorbic acid was used as a standard , which showed IC 50 Conclusio n: Findings indicate that this plant is a good source of antioxidant and can be used for the treatment of diseases as such medicinal plant extracts are natural products and they are comparatively safe, eco -friendly, less expensive and locally available. Hence, the validation of the effects of these herbal remedies will have to be undertaken for their wider acceptance.Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|
Articles Abstract Database | School of Pharmacy Archieval Section | Not for loan | 2020890 |
Objective:
The main objective of this study was to evaluate the free radical scavenging activity of methanol
(70%)
and aqueous extract of
G.
montana
leaves
which is a
traditionally used herb known for
its hepatoprotective activity
.
Method
s:
The
in vitro
antioxidant
activity
of
G. montana
extract
was determined using
1, 1
-diphenyl
-2-picrylhydrazyl radical (DPPH)
,
2,2
′
-azin
obis
-
(3
-ethylbenzothiaziline
-6-sulfonate (ABTS), Hydrogen p
eroxide scavenging activity
, Superoxide anion radical scavenging activity and Reducing
Power ability at
three
different concentrations
(1.78μg
/ml
, 3.57μg/ml
and 7.14μg/ml
).
Result
s:
The
Result
s revealed similar observations
between the methanol and aqueous extract with respect to standard and showed potent
antioxidant activity. Ascorbic acid was used as
a standard
, which showed IC
50
Conclusio
n:
Findings
indicate
that this
plant is a good source of antioxidant and can be used for
the
treatment
of diseases as
such
medicinal plant
extracts are natural products and they are comparatively safe, eco
-friendly, less expensive and locally available. Hence, the validation of the effects
of these herbal remedies will have to be undertaken for
their wider acceptance.
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